TRANSECT allows users to query large collections of cohort transcriptomic data to assess global gene expression changes given disparate expression of their gene (or genes) of interest. TRANSECT works by defining two groups within a cohort based solely on the expression of a gene or a gene set and subsequently compares the groups for global expression changes and functional differences. TRANSECT outputs descriptive statistics about the genes of interest followed by differential expression results and resulting matches to gene set collections.

Please see the TRANSECT manuscript for details and example case studies.